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“A substantial part of the skill of the experimenter lies in his choice of factors to be randomized out of the experiment. If he is careful, he will randomize out all of the factors which are suspected to be causally important but which are not actually part of the experimental structure. But every experimenter necessarily neglects some conceivably causal factors; if this were not so, the randomization procedure required would be impossibly complicated.” — M.G. Kendall & A. Stuart